Susceptibility of streptococci to antibiotics and biocides isolated from Saudi Arabia and UK

Abstract number: 1733_193

Al-Qorashi A.M.

The assessment of the in vitro activities of 16 antibiotics, 10 biocides and 6 metallic compounds against clinical isolates of Streptococcus pyogenes (group A) from UK and Saudi Arabia and its control strains from UK.

16 antibiotics (benzypenicillin, erythromycin, lincomycin, methicillin, rifampicine, trimethoprim, vancomycin, ampicillin, chloramphenicol, fucidic acid, gentamicion, kanamycin, nalaedixic acid, novobiocin and streptomycin), 10 biocides (3 phenolics: chlorocresol, cresol, phenol; 4 parabens: methyl, ethyl, butyl and propyl esters of para-4-hydroxybenzoic acid); a bisbiguanide: chlorhexidine diacetatate; 2 quaternary ammonium compounds: cetylpyridinium chloride and benzethonium chloride) and 6 metallic compounds (mercuric chloride, phenylmercuric nitrate, cadmium chloride, cupric chloride, zinc chloride and silver nitrate) were tested against controls and clinical isolates of Streptococcus pyogenes (group A) from the university hospital of Wales UK as well as clinical isolates from King Fahd University Hospital, Al-Khobar and King Abdulaziz University Hospital, Jaddah, Saudi Arabia by the disc diffusion method and the determination of minimal inhibitory concentration (MIC).

All strains of Streptococcus pyogenes (group A) were b-lactamase-negative. All British strains were sensitive to all of the antibiotics tested, except gentamicin and streptomycin. Some of the Saudi strains were resistant to gentamicin and erythromycin and all were resistant to lincomycin. The British and Saudi Arabian strains showed the same order of response to phenols and parabens. Similarly, the British and Saudi Arabian strains were equally sensitivity to phenylmercuric nitrate, however, response to other metallic compounds were variable.

Session Details

Date: 31/03/2007
Time: 00:00-00:00
Session name: European Society of Clinical Microbiology and Infectious Diseases
Location: ICC, Munich, Germany
Presentation type:
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