Analysis of IgG and IgM in patients pre-diagnosed with toxoplasmosis

Abstract number: 1733_27

Sönmez Tamer G., Mutlu B., Willke A.

Objectives: The aim of this study was to compare Toxoplasma seropositivity among the regions of Turkey. For this purpose, we evaluated toxoplasma IgG and IgM seroprevalans retrorespectively from patients who applied to gynecology, neonatalogy, paediatric and other clinics. Serum which were obtained from patients who are prediagnosed with Toxoplasma were included to this study. These serum samples were collected between 01.2003–10.2006.

Methods: Serums tested with Enzyme Immune Assay (Axsym, Abbot^®) for IgG and IgM. Data were collected and documented for a period of 3 years.

Results: The results obtained were evaluated in four groups: group 1 gynecology, group 2 neonatal, group 3 paediatric and group 4 others. In 1828 serum samples, we found 32.67 IgG seropositive, 1.25% IgM seropositive and 5.47% IgG+IgM seropositive samples. In 256 serum samples from gynecology 47.65% were IgG seropositive, 1.95% were IgM seropositive and 5.85% were IgG+IgM seropositive. In 239 serum samples from paediatric clinic 50.20% were IgG seropositive, and 1.23% were IgG+IgM seropositive, but fail to find IgM seropositive. In 280 serum samples from neonatal clinic we found 43.57% were IgG seropositive but fail to find IgM and IgM+IgG seropositive samples. In 1053 serum samples from other clinics 22.13% were IgG seropositive, 1.70% were IgM seropositive and 7.79% were IgG+IgM seropositive.

Discussions: Toxoplasma IgG seroprevalance in Kocaeli region were found to be lower than eastern and middle Anatolian parts of Turkey where animal farming is a common practice. The results obtained from this study may indicate that the observed differences may be related to the high socioeconomic status of people better hygiene rules and sanitation in Kocaeli region than other regions.