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Legionella spp. causing community-acquired pneumonia in Germany. Data from the Competence Network for Community-Acquired Pneumonia (CAPNETZ)

Abstract number: 1732_173

von Baum H., Marre R., Gonschior S., Welte T., Lück C.

Objectives: Prevalence, clinical data and outcome of Legionella pneumonia (LP) in 2503 patients from ten clinical centres with community acquired pneumonia (CAP), participating in the German multicentre study of the Competence Network for Community Acquired Pneumonia (CAPNETZ) were analysed.

Methods: All demographic, clinical and diagnostic data of the patients were recorded using standardised web-based data sheets. Work up of respiratory samples included identification of bacterial microorganisms as well as PCR for C. pneumoniae, M. pneumoniae, Legionella spp. and viral pathogens. Urine was tested for the presence of S. pneumoniae and L. pneumophila antigen. Relevant results from serologic tests were considered.

Results:Legionella spp. was diagnosed in 105 (4.2%) patients and thus represented after S. pneumoniae the second most frequent identified pathogen causing pneumonia. Patients with LP were predominantly older men, suffered more often from diabetes, were heavier smokers and produced more often respiratory samples, which were less often purulent. They received more often antibiotic substances with activity against atypical bacteria. Although 85% of the patients had a CRB 65 score of 0 or 1, respectively, 14 patients (13.3%) with LP expired.

Conclusion:Legionella spp. is a relevant pathogen causing CAP in Germany and is associated with a serious clinical course.

Session Details

Date: 31/03/2007
Time: 00:00-00:00
Session name: European Society of Clinical Microbiology and Infectious Diseases
Subject:
Location: ICC, Munich, Germany
Presentation type:
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