Determination of anti-HBS titre mean induced by hepatitis B vaccine among health care workers in an Iranian hospital

Abstract number: r2270

Talebi Taher  M.


HBV is a major cause of viral hepatitis, cirrhosis and liver cancer worldwide. Health care workers are one of the high-risk groups in affecting and transmission of this virus.


In this descriptive cross-sectional study, 102 HCWs of firoozgar hospital including faculty members, residents, interns, students, nurses and clerks were selected and enrolled through convenience sampling. All participants had to complete three-dose vaccination schedule. After blood sampling the samples were transferred to laboratory. Check list was consisted of age, sex, occupational group, smoking, alcohol abuse chronic renal and hepatic failure , diabetes and duration after the last dose of vaccine.


Statistical analysis was done with SPSS 11.5 software. P < 0.05 was considered statistically significant. Multiple linear regression model was used to predict effecting factors on Anti-HB titre .102 Anti-HBS titres of HCWs were determined and the mean was 70.43(95% CI, 57.02–83.84). Also, Anti-HBS titres of 30 individuals (29.4%)were less than 10 mIu/ml and 72 individuals (70.6%) were equal or more than 10 mIu/ml. There was a significant statistical correlation between Anti-HBS titre and age and duration after the last dose of vaccine (p < 0.05).


Following-up for complete three-dose injection, vaccination before or at the onset of working should be attended. HCWs who are one of the high-risk groups in affecting and transmission of HBV, are recommended to determine their Anti-HBS titre after three-dose vaccination.

Session Details

Date: 01/08/2007
Time: 00:00-00:00
Session name: XXIst ISTH Congress
Location: Oxford, UK
Presentation type:
Back to top