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Nosocomial bloodstream infections in the cardiovascular surgery centre, Iasi, Romania

Abstract number: p1005

Mereuta  A., Dan  M., Colar  L., Tinica  G., Georgescu  G.I.M., Buiuc   D.

Objectives: 

To analyse the aetiology, the origin, epidemiological features and outcome of nosocomial bloodstream infections (NBSI) in patients that underwent cardiovascular surgery.

Methods: 

A retrospective study of bloodstream infections was conducted between April 2001 and September 2005 in the Cardiovascular Surgery Centre of Iasi.

Results: 

There were 57 episodes of nosocomial bloodstream infections at 2068 admissions. Bloodstream infections were secondary to an infectious body site (lower respiratory tract, wound, urinary tract) in 35.08% of the episodes, catheter-related in 22.80% and in 42.10% of cases they had an unknown origin. Cell-wall deficient forms (45.61%) were the most prevalent microorganisms (26 strains, out of which 12 reverted to the classical state: 4 gram-positive cocci, 6 gram-positive bacilli, 1 Gram-negative bacilli, 1 anaerobe and 14 were L-stable), followed by Staphylococcus aureus and coagulase-negative staphylococci 12 strains (21.05%), gram-positive bacilli 11 (19.29%), fungi 8 (14.03%), HACEK group, gram-negative bacilli, Enterococcus spp. 3 strains each (5.26%), Streptococcus pneumoniae 2 (3.50%), anaerobes 1 (1.75%). The proportion of polymicrobial episodes was 3.5% (Staphylococcus aureus Haemophilus paraphrophilus and H. parainfluenzae + Enterococcus faecalis) and fatality was 26.3%.

Conclusions: 

We found a high proportion of cell wall deficient forms, rarely reported before. This may be due to: blood culture collection under antimicrobial therapy (P = 0.016), especially beta-lactams; more adequate methods for blood culture processing: sucrose enriched media (Hemoline Performance Duo, bioMerieux, France) and acridine orange stain for microscopy of the blood culture.

Session Details

Date: 01/08/2007
Time: 00:00-00:00
Session name: XXIst ISTH Congress
Subject:
Location: Oxford, UK
Presentation type:
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