Diabetic foot infections: the evolving characteristics, microbiology and determinants of mortality

Abstract number: o124

Gündes  S., Yulugkural  Z., Biyikli  M., Buyukarslan  B.


Foot infections in patients with diabetes mellitus are among the most common bacterial infections encountered in our clinical practice. The aim of the present study was to evaluate aetiology, medical outcomes, including risks for complications and mortality, in 68 adult patients hospitalized for severe DFI.


This report describes a retrospective analysis of medical records of 68 hospitalized patients who had been admitted or consultated to Infectious Diseases Department for severe DFI from January 2004 to November 2005 in a University hospital.


There were 40 males and 28 females. Average patient age was 51.8 years. Most of the patients were in level 1, 2, or 3 on Wagner Scale, only 23 (33.8%) of patients had combined osteomyelitis and deep soft tissue infection. Forty-seven bacteria were documented microbiologically in 39 cases (57.3%). Staphylococcus aureus and Enterobacteriaceae being the most common isolates. Overall, 25 patients (36.7%) were discharged early (< 14 days) and 43 patients (63.2%) were hospitalized for more than 14 days. Of these, 51 required early surgical debridement (75%), 23 (33.8%) underwent at least one digit amputation. Amputation was more common with level 4 patients (62%) compared with those who had SSTI (30%) only. Overall mortality was 14% factors associated with death were male sex, presence of multiple comorbid conditions, congestive hearth failure, morbid obesity, hypoalbuminaemia, renal insufficiency, and shock.


DFIs are serious bacterial diseases that are often underestimated and poorly recognised. Our findings indicate that deep foot infections in patients with diabetes was a heterogeneous entity, in which type and severity is related to choice of treatment strategy and to outcome.

Session Details

Date: 01/08/2007
Time: 00:00-00:00
Session name: XXIst ISTH Congress
Location: Oxford, UK
Presentation type:
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