Diabetes mellitus and 30-day and 90-day mortality after hospitalization with pneumonia: a population-based follow-up study of 41 793 adult patients
Abstract number: o121
Thomsen R.W., Brommann J., Riis A., Lervang H.-H., Schønheyder H.C., Sørensen H.T.
Diabetes may be associated with increased mortality after pneumonia due to decreased immunity, impaired lung function, and hyperglycaemic derangement. We examined diabetes as a predictor of 30-day and 90-day mortality in a large cohort of adult patients hospitalized with pneumonia.
Population-based cohort study in the three Danish counties of North Jutland, Viborg and Aarhus between 1994 and 2003. Patients with a first-time hospital discharge diagnosis of pneumonia were identified in hospital discharge registries. Information on diabetes and comorbidities was obtained from discharge registries and prescription databases. All patients were followed for 90 days after hospitalization through the Danish Civil Registration System. We compared mortality rates in patients with and without diabetes, adjusted for gender, age, and comorbidity.
A total of 41 793 adult patients were hospitalized with pneumonia (median age 74 years); of these, 3928 patients (9.6%) had diabetes. Overall mortality in diabetic patients compared with other patients with pneumonia was 18.7% vs. 14.8% after 30 days, and 26.5% vs. 21.4% after 90 days. After adjustment, mortality rates in patients with diabetes were only marginally increased (mortality rate ratio = 1.12 (95%CI: 1.041.21) after 30 days, and 1.09 (95% CI: 1.021.16) after 90 days) compared with non-diabetic pneumonia patients.
Our results corroborate previous reports suggesting that diabetes has only a very limited influence on outcome in patients hospitalized with pneumonia.
|Session name:||XXIst ISTH Congress|
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