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Tuberculosis and diabetes: risks and realities

Abstract number: 1135_182

Bygbjerg I.C.

The vicious combination of tuberculosis (TB) and HIV is now well-established, though not well-controlled. More unnoticed is the meeting between TB and diabetes, predominantly type 2 (DM2,) particularly in low-income countries in fast transition. In India, e.g., about 10% of adults have DM2 and another 10% pre-stages (impaired glucose-tolerance), while 1% may have active TB and 30% have are at risk of (re-)activating TB. In Mexico, the risk for reactivating TB in patients with DM2 was increased 4–6 times, which is comparable with increased risk for TB among HIV-infected. The World Health Organisation preview that by year 2025 about 350 mio. may have DM2, more than 70% in developing countries. It remains to be seen if TB may double or quadruple in the wake of the DM2 epidemic, as has been the case with TB in HIV. The mechanism(s) behind the increased risk for re-activation of TB in DM is poorly understood. Present knowledge (and lack thereof) will be highlighted and suggestions given for future research and possible measures to control this emerging health problem.

Session Details

Date: 01/08/2007
Time: 00:00-00:00
Session name: XXIst ISTH Congress
Subject:
Location: Oxford, UK
Presentation type:
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