The anti-candidal activity of Pseudomonas aeruginosa strains isolated from clinical specimens
Abstract number: 1135_146
Kaleli I., Cevahir N., Demir M., Yidirim U., Sahin R.
To investigate in vivo and in vitro the anti-candidal activity of Pseudomonas aeruginosa strains against Candida species.
Forty-four P. aeruginosa strains isolated from various specimens of intensive care patients in the study. Candida albicans ATCC 10231, C. parapsilosis ATCC 22019, C krusei ATCC 6258 and a clinical isolate of C. tropicalis were used as Candida strains and anti-candidal activity of the strains were examined by using Kerr's method.
The total inhibition rates obtained by using blood agar for C. albicans, C. parapsilosis, C. krusei and C. tropicalis were 41%, 34%, 34% and 25%, respectively. These rates were 45%, 39%, 48% and 25%, respectively when Sabouroud dextrose agar used. In mice model of concomitant subcutaneous infection with Candida species and P. aeruginosa, no yeast was recovered from skin cultures despite 100% detection of P. aeruginosa.
P. aeruginosa strains isolated from intensive care patients showed anti-candidal activity against these Candida species and it can be important for the treatment of the patients.
|Session name:||XXIst ISTH Congress|
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