Back

The anti-candidal activity of Pseudomonas aeruginosa strains isolated from clinical specimens

Abstract number: 1135_146

Kaleli I., Cevahir N., Demir M., Yidirim U., Sahin R.

Objective:  

To investigate in vivo and in vitro the anti-candidal activity of Pseudomonas aeruginosa strains against Candida species.

Methods:  

Forty-four P. aeruginosa strains isolated from various specimens of intensive care patients in the study. Candida albicans ATCC 10231, C. parapsilosis ATCC 22019, C krusei ATCC 6258 and a clinical isolate of C. tropicalis were used as Candida strains and anti-candidal activity of the strains were examined by using Kerr's method.

Results:  

The total inhibition rates obtained by using blood agar for C. albicans, C. parapsilosis, C. krusei and C. tropicalis were 41%, 34%, 34% and 25%, respectively. These rates were 45%, 39%, 48% and 25%, respectively when Sabouroud dextrose agar used. In mice model of concomitant subcutaneous infection with Candida species and P. aeruginosa, no yeast was recovered from skin cultures despite 100% detection of P. aeruginosa.

Conclusion:  

P. aeruginosa strains isolated from intensive care patients showed anti-candidal activity against these Candida species and it can be important for the treatment of the patients.

Session Details

Date: 01/08/2007
Time: 00:00-00:00
Session name: XXIst ISTH Congress
Subject:
Location: Oxford, UK
Presentation type:
Back to top