Predictors of outcome in patients with blood-stream infections
Abstract number: 1135_107
Ayaz C., Celen M.K., Geyik M.F., Hosoglu S., Ulug M.
To evaluate the epidemiology and risk factors of bloodstream infections (BSI), to determine the mortality associated BSIs and identify independent predictors of mortality.
This study was performed retrospectively, at the hospital from April 2002 to November 2002.
324 patients with BSI were enrolled to the study. Mean age was 41.7 ± 23.1 years old, and 196 (60.5%) were male. During study period 407 episodes occurred, of which 47.4% were nosocomial bacteraemia, 25.8% were community acquired bacteraemia, 22.2% represented contamination and 4.6% represented transient bacteraemia. Gram positive microorganisms were the most commonly isolated microorganisms (66.5%). Nosocomial BSI occurred in 134 (41.3%) patients. The most common pathogens nosocomial BSI group were coagulase negative Staphylococcus (29.2%), S. aureus (23.5%), E. coli (11.9%), Acinetobacter spp. (6.4%), P. aeruginosa (5.6%) and Klebsiella spp. (5.1%). Methicillin resistance was detected in 58% of staphylococcus isolates in nosocomial BSI group. 18.7% of the patients died. Mortality rate associated with bacteraemia obtained as 14.8%. Mortality rate in nosocomial BSI group obtained as 33.4%. Multivariate analysis revealed nosocomial acquisition, age > 60 years, hospital stay more then 7 days, stay in intensive care unit as factors associated with mortality rate.
These results indicate that eliminate factors influencing the outcome of bacteraemia especially in nosocomial bacteraemia. The prevention of nosocomial infections and appropriate antibiotic treatment can improve the prognosis of patients.
|Session name:||XXIst ISTH Congress|
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