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Trends in antimicrobial resistance in urinary isolates of E. coli from patients hospitalised at a teaching hospital Maribor, Slovenia

Abstract number: 1134_04_209

Saletinger R., Baklan Z., Gorisek Miksic N., Novak D.

Objective:  

To assess the prevalence and trends in antimicrobial resistance in urinary isolates of E. coli.

Methods:  

We studied resistance rates to different antimicrobial agents in urinary isolates of E. coli from patients hospitalised at Teaching Hospital Maribor, Slovenia in years 1998, 2000 and 2003. The isolation was performed by standard methods . Susceptibility was determined by disc diffusion test according to the NCCLS.

Results:  

Results are collected in Tabel 1.

Conclusion:  

E. coli remains the most common uropathogen representing between 39% to 40.3% of all urine isolates.We have noticed significant increase in resistance rates in E. coli strains to some commonly used antibiotics in the last six years. Susceptibility to amoxicillin–clavulanate, cephalosporins of second and third generation and aminoglycosides remained stable, although the resistance rates to trimethoprim–sulfamethoxazole and ciprofloxacin are increasing very rapidly. We believe that surveillance of antimicrobial resistance is very important for giving recommendations about empirical antibiotic treatment.

Table 1  Resistance rates of E. coli isolates to different antimicrobial agents in the years 1998, 2000 and 2003

Year1998,02000,02003,0*P value
Total number of Isolates256323272456 
Percentage of E.coli (%)39,139,440.3 
Resistance rates of E.coli (%)%%% 
Amoxicillin/ampicillin39,538,443,10,0230
Amoxicillin clavulanate15,410,514,0NS
Cephalotin7,85,711,90,0046
Cefaclor2,82,22,7NS
CeftriaxonND0.80.8NS
Ciprofloxacin4,96,911,90.0001
Gentamicin2,32,23,5NS
Cotrimoxazole15,018,422,00,0001
*P value of chiquadrat test, NS not statistically significant. ND No Data.

Session Details

Date: 01/08/2007
Time: 00:00-00:00
Session name: XXIst ISTH Congress
Subject:
Location: Oxford, UK
Presentation type:
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