Chronic fatigue syndrome

Abstract number: 1134_04_182

Cecchini E., Greco M., Acuña S.

Objective:  

To describe frequency of clinical and epidemiological features in outpatients chronic fatigue syndrome (CFS).

Methods:  

A retrospective observational study was performed. A cohort of 25 patients fulfilling the Centers for Disease Control and Oxford, UK criteria (1994) for CFS was included.

Results:  

Eighteen patients were female (72%) and 28% male (p < 0.001, RR 2.6) with a mean age for women 37.5 ±11.7 years and for male patients 38.3 ± 7.6 years. The mean time before the first consult to the Institute was 6.3 months. Prior history of C. trachomatis infection was related in 27.7% women and 28.6% men and allergic condition in 44.4% and 57.1% respectively. In the following table are synthesized the frequency of subjective symptoms. In all patients serology was no reactive for HBV, HCV, HIV e IgM CMV. Positive serology was found for IgG toxoplasmosis (84%), IgG EBV (80%), EA EBV (32%) and brucellosis (4%). Total immunoglobulin was increased in 20% and lowered in 24%. Multitest (7/8) showed hypo or anergy in 77.8%. Active lymphocytosis was a finding in 32% and increased liver enzymes in 24%.

Conclusions:  

This syndrome affects quality of life and status performance in the productive age group. There was net predominance of women. It must be noted the high incidence of prior history of infection for C. trachomatis when compared with general adult population (3–5%) in our country.