Two consecutive point prevalence studies on indications for antibiotic use in selected Latvian hospitals

Abstract number: 1134_01_121

Pujate E., Vigante D., Kvista E., Pavlovska D., Mironovska A., Lama I., Nikitina O., Kula M., Snipe R., Zeidaka L., Dumpis U., for the Latvian Nosocomial Infection Study Group 


The objective of these surveys was to test simple surveillance system for the assessment of the prevalence of nosocomial infection and use of antibiotics.


Seven and nine Latvian hospitals were included in years 2003 and 2004 respectively. One trained personnel in each hospital has visited all clinical departments over the month (May) period. All administered antimicrobials were recorded according to the purpose of the administration: treatment of community and hospital acquired infection, prophylaxis, or the purpose was unclear to investigator. Data were double entered and analysed by EpiData 3.02 and Epi Info 2000 software packages.


The number of patients treated with antibiotics was 855 (28.9% out of 3150 in 7 hospitals) and 988 (26.2% out of 3776 in 9 hospitals) in years 2003 and 2004 respectively. The prevalence of patients treated for nosocomial infection was 3.6% in both 2003 and 2004. In 21% (2003) and 12% (2004) of patients antibiotics were prescribed without clear clinical indications. Five most commonly used antibiotics were cefazolin (26% of all antibiotics in 2003 and 22 % in 2004), gentamicin (11% and 10%), ampicillin/amoxicillin (14% and 12%), metronidazole (9% and 8%), and ciprofloxacin (9% and 7%). Ten different antibiotics were used for surgical prophylaxis. Cefazolin accounted for 58% and 63% from them in 2003 and 2004 respectively. For treatment of infection most commonly used antibiotics were cefazolin (19% and 14%), ampicillin/amoxicillin (15% and 14%), and gentamicin (12% and 11%).


Surveillance protocol was equally applicable for all hospitals. The results of the study indicate the main problems in antibiotic prescription: overuse of antibiotics, inconsistent surgical prophylaxis, and different pattern of empirical choice in various hospitals. It also gives an insight for the problem of nosocomial infections in Latvian hospitals.

Session Details

Date: 01/08/2007
Time: 00:00-00:00
Session name: XXIst ISTH Congress
Location: Oxford, UK
Presentation type:
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