Comparison of two different therapeutic regimens of DOT strategy in patients with pulmonary tuberculosis
Abstract number: 903_r2344
To compare the effect, complication, and treatment cost of two different therapeutic regimens of DOT's strategy in treating patients with pulmonary tuberculosis (TB) and positive sputum smear test.
A clinical trial was done on 200 patients aged 1550 years with pulmonary tuberculosis and no history of previous treatment for TB, Immunocompromise, liver, and kidney diseases. (pregnant women excluded from this study) Selected patients divided into two groups randomly and one group was treated by using the Denver method (62 doses), and the other group treated with routine standard method (180 doses), Sputum smear test was performed for each patient at the end of 2, 4, and 6 months of treatment, and finally collected data were analysed by SPSS software and Fisher method (P < 0.05).
Cure occurred in 94% of patients treated by Denver method and in 93% with routine standard method, this result was not significant, also we could not find significant difference in complications occurred during using these two methods. (9% in Denver method vs. 6% in standard method)
With regard to using drugs just twice a week in Denver method and its lower cost treatment, Denver method will be better than standard method and patients compliance will be more in this method."
|Session name:||XXIst ISTH Congress|
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