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Viral aetiology of acute lower respiratory infections among hospitalised children in Greece

Abstract number: 903_r2332

Antonaki G.

"
Objectives:

The viral aetiology of acute lower respiratory infections (ALRIs) in hospitalised children under 3 years of age was studied.

Methods:

During the winter seasons from 1998 to 2003, 1847 children with ALRIs were tested for the determination of the responsible aetiologic viral agent. Nasopharyngeal aspirates (NPAs) were analysed for the common respiratory viruses antigen detection (RSV, influenza A (IA) and B (IB), parainfluenza (PIV) 1 + 2 and 3 and adenoviruses), using indirect immunofluorescence assay (IFA).

Results:

Viral agents were associated in 1032 of 1847 ALRIs cases (56%). The annual occurrence of viral ALRIs with the respiratory viruses detected is showed in Table 1:

RSV was identified in 933 NPA samples (90,4% of all viral diagnoses). Influenza A virus (5%), adenovirus (1.6%), influenza B (1.5%), PIV (1 + 2) (0.9%) and PIV3 (0.7%) accounted for 9.6% of the viral diagnoses. RSV was prevalent in children under 1 year of age (99%).

Conclusions:

RSV is the main aetiologic agent of viral ALRIs in young hospitalised children.

 199819992000200120022003Total (n)
 n %n %n %n %n %n % 
RSV88 46.393 46.5164 49.5214 56.5220 62.3154 39933
Adeno1 0.530 01 0.31 0.31 0.312 316
IA7 3.72 112 3.63 0.87 22.1 5.352
IB0 00 00 00 014 41 0.2515
PIV (t+2)0 00 00 00 01 0.38 29
PIV 30 01 0.51 0.31 0.32 0.62 0.57
Total positive 96  96  178  219  245  198 1032
Total samples 190  200  331  379  353  394 1847
Positive samples (%) 50.5  48  53.8  57.8  69.4  50.25 56
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Session Details

Date: 01/08/2007
Time: 00:00-00:00
Session name: XXIst ISTH Congress
Subject:
Location: Oxford, UK
Presentation type:
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