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Chlamydia trachomatis infections in a Northwestern Greece population

Abstract number: 903_r2243

Levidiotou S.

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Objectives:

Worldwide, Chlamydia trachomatis is one of the most common sexually transmitted bacterial pathogens. The aim of the present study was to determine the prevalence of C. trachomatis in adult women and men in Northwestern Greece using a highly sensitive PCR-based diagnostic assay.

Methods:

2672 symptomatic and asymptomatic women aged 18–55 years and 214 symptomatic men aged 18–65 years not attending sexually transmitted disease (STD) clinic were enrolled in this study from November 1998 to December 2003. Two types of specimens were collected from each patient: cervical swab and first-void urine (FVU) from women, urethral swab and FVU from men. All these specimens were examined with the automated amplification system: PCR Cobas Amplicor, CT-PCR test (Roche Diagnostic Systems). Also, laboratory diagnosis for common STDs, and collection of demographic information and behavioural data were performed.

According to our results, C. trachomatis was detected in 46 women (1.72%) and 10 men (4.67%). As regard female population, 65% of them were married, 64% did not use condom, 12% were pregnant. Most commonly identified sexually transmitted pathogens were Gardnerella vaginalis (45%), and Candida (14%), while Trichomonas vaginalis infection was found in 3%, and HPV in 0.5% of the women tested. As regard male population, 51% of them were married, 73% did not use condom, and one man had coinfection with N. gonorrhoeae. Among patients with C. trachomatis infection, the majority of them (88%) were young (under 30 years), 67% of them reported more than one sexual partner within the last year, and 94% of the women had urogenital symptoms. As regard the type of specimen, cervical swab specimens were slightly more sensitive than FVU for the detection of C. trachomatis infection in women, and FVU compared with urethral swab in men. In case of couples tested, screening males alone detected 80% of the infected couples. After appropriate treatment, all C. trachomatis infected patients had negative result in the follow-up visit. Repeated infections with C. trachomatis were not detected.

In conclusion, the prevalence of C. trachomatis infection in our geographic area is low. In standard clinical practice, there is need to screen both males and females, and test two types of specimens, urogenital swab and urine.

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Session Details

Date: 01/08/2007
Time: 00:00-00:00
Session name: XXIst ISTH Congress
Subject:
Location: Oxford, UK
Presentation type:
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