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A 2-year survey of K. pneumoniae isolates at a new teaching hospital in Turkey

Abstract number: 903_r1995

Begendik F.

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Objective:

To determine the antibiotic susceptibilities and the prevalence of ESBL production in K. pneumoniae isolates 2 year.

Methods:

A total of 207 isolates (107 urine, 36 wound, 21 genital, eight blood, 14 sputum, 11 drain and 10 others) were investigated. Isolates were identified with conventional methods. Antibiotic susceptibility was determined by Kirby–Bauer disc-diffusion method according to NCCLS. ESBL production was determined by double disc synergy test (DDS) and confirmed by Etest (AB BIODISK, Sweden).

Results:

Ratio of ESBL producing strains was 23/207 (21.7%). Among ESBL producing strains 75.5% of the isolates were recovered from inpatients. Susceptibility to cephalosporins were 0–37% in ESBL-producing strains and 82–94% in non-ESBL producing strains. ESBL-producing strains were 20% more resistant to ciprofloxacin. Isepamicine was the most effective (100%) aminoglycoside antibiotic against ESBL-producing strains. Karbapenem resistance was not observed.

Conclusion:

Depending on the high prevalence of ESBL-producing strains of K. pneumoniae in nosocomial infections, clinical microbiology laboratories must effectively detect and report the presence of ESBL routinely. DDS is reliable, cheap and not much time consuming test for detecting ESBL production in routine use.

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Session Details

Date: 01/08/2007
Time: 00:00-00:00
Session name: XXIst ISTH Congress
Subject:
Location: Oxford, UK
Presentation type:
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