The aetiologic agents of onychomycosis in Latvia
Abstract number: 902_p1776
Onychomycosis is a global problem. From 5 to 20% of inhabitants suffer from fungal nail infections. The causative agents are classified in different groups dermatophytes, moulds and yeasts. The dystrophic nails harbour a large amount of bacteria and secondary invading yeasts and moulds. The role of moulds and yeasts in aetiology of onychomycosis or aggravation of the condition is quite questionable. The aim of this study was to establish the main causative agents of fungal nail infection in Latvia. Before this there was no research about onychomycosis in Latvia about the main causative agents, optimal diagnostic methods, susceptibility to the clinically used antifungal preparations.
The present research work was done at the laboratory of The State Centre of Skin and sexually transmitted diseases within last 3 years. In the research were involved 671 patients with clinically changed nails and suspicion to onychomycosis. Microscopy and cultivation methods were used (Mycoline, bioMerieux) with further identification of Candida spp. by Fungi fast/twin (Arbor medical).
The presence of pathogenic fungi was confirmed for 511 patients (76.15%). The most often causative agent was Trichophyton rubrum (64%) as being the only causative agent of monoinfection and T. rubrum in mixed infection with C. spp., Penicillium spp.and Aspergillus spp. (5.65%). Other dermatophytes (Epidermophyton floccosum) and different species of Trichophyton (T. mentagrophytes, T. tonsurans) were detected (2.72%). Totally the dermatophytes as the causative agents of onychomycosis were isolated in 72.37%. The second largest group of causative agents was Candida spp. (17%). The moulds were isolated in the remaining 10.63%.
Tinea unguis most often is caused by dermatophytes T. rubrum and T. mentagrophytes. C. albicans and C. parapsilosis are the main causative agents from yeasts. From nondermatophytes the most often isolated was Scopulariopsis brevicaulis."
|Session name:||XXIst ISTH Congress|
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