Mediterranean spotted fever: study of 29 cases

Abstract number: 902_p1663

Louro E.


Mediterranean spotted fever also known as boutonneuse fever is an estival endemic zoonosis in the Mediterranean region. The dog tick, Rhipicephalus sanguineus, does the accidental transmission of Rickettsia conorii to men.


The authors claim to demonstrate the distribution of the disease in a Medicine Department during the period 1993-2003 relatively to sex, age, clinical symptoms, residence, job, animal contacts, seasonal distribution, ‘tache noire’ location, analytical alterations, complications and treatment.


Retrospective study of Mediterranean spotted fever between 1993 and 2003 in the Medicine III Department of Coimbra University Hospital.


The peak incidence occurred during summer season, both sexes were equally reached with a predominance on the sixth and seventh decades of life. The ‘tache noire’ was not observe in all patients and the main clinical manifestations were fever and maculopapular rash involving the palms and soles. The more frequent laboratory alterations observed were: increased AST and ALT, thrombocytopenia and hiponatremia. The common complications were: shock, pneumonia and disseminated intravascular coagulation. Ten of the 29 patients had a positive serological result for R. conorii. Treatment with doxycycline was the most frequent adopted.


Generally, boutonneuse fever is a benign disease but, as it can progress to severe ill (shock, pneumonia) and lead to significative increase in mortality, is advisable to maintain a close follow-up of this cases.


Session Details

Date: 01/08/2007
Time: 00:00-00:00
Session name: XXIst ISTH Congress
Location: Oxford, UK
Presentation type:
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