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Bacterial vaginosis in patients with genital HPV infection

Abstract number: 902_p1609

Kuch A.

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Objectives:

Human papillomavirus (HPV), particularly HPV 16 and 18, is now recognised as the main cause of cervical cancer. It has been suggested that bacterial vaginosis and altered vaginal flora may be a risk factor for sexually transmitted diseases (STD). The aim of study was relationship between genital HPV infection and bacterial vaginosis.

Methods:

This study were performed on 120 women between 21 and 42 years of age and sexually active. Vaginal flora was examined by Gram's stain, standardised scoring criteria (Nugent's score). Bacterial vaginosis was diagnosed if a score was 7–10, a score of 4–6 indicated intermediate vaginal flora and a score of 0–3 normal vaginal flora. In addition, presence of Lactobacillus spp. and Gardnerella vaginalis was confirmed by culture. HPV DNA type: 16 and 18 was detected using PCR amplification assay (amplification of DNA fragment which encoded E6 gene). Results: In the group of 120 women, 56 had bacterial vaginosis and intermediate vaginal flora, including 10 with HPV16 infection. The remaining 64 patients manifested normal vaginal flora and only 1 had signs of HPV16 infection. None of the patients had DNA HPV18.

Conclusions:

The results indicate that women with genital HPV oncogenic type infections are at increased risk for BV.

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Session Details

Date: 01/08/2007
Time: 00:00-00:00
Session name: XXIst ISTH Congress
Subject:
Location: Oxford, UK
Presentation type:
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