Genetically modified are helpful to gain knowledge regarding various biological mechanisms that can result in hearing impairment. Because behavioral tests are difficult and time consuming, generally for assessment of what mice can hear measures of neural responses such as cochlear microphonic, thresholds of units in the inferior colliculus and, most commonly, auditory brainstem response (ABR) are used. However, the thresholds for the ABR and behavioral audiometry (BA) in mice are not only quite different, but there is no simple relationship between them. Thus, ABR cannot be used to predict BA with any accuracy. On one hand the reason for this is that the tones used in ABR cannot be pure since they have to have very rapid onsets, which causes "spectral splatter". On the other hand BA uses tone durations of about 400 ms that are pure and allowing temporal integration. Thus, BA appears to have some fundamental advantages over ABR. Consequently I realized a "plug and play" system for BA that relieves potential users from considering technical details behind the method. The system includes a sound-prove box, all required electronics and software, thus, just labspace (2.5 x 2.5 m) and a computer is needed.