Objective: 

The role of magnesium in diabetes is still controversial in many studies. Therefore, we investigated the status of magnesium in normal versus diabetic subjects and patients with elevated concentration of blood glucose (non-diabetic). It seems interesting to know that diabetic subjects have a decrease in magnesium level in order to introduce an appropriate alimentation in these patients to reduce glucose metabolism disorder.

Methods: 

Eighty subjects (women and men) aged 35 to 60 years were examined. All subjects underwent to clinical evaluation, blood sample measurements. The blood glucose concentration, HbA1C and the concentration of urine glucose were measured. The lipidic profiles of all subjects were also identified. The patients were classified in groups according the Body Mass Index (BMI), the blood glucose, age and sex.

Results: 

No statistically significant diffference was found between patients with diabetic disease, patients with increased blood glucose or normal subjects. These results were found after studying magnesium concentration in each group according to each parameter (BMI, blood glucose, age and sex).

Conclusions: 

Our prospective study has permitted to show that the blood concentration of magnesium is not a definite factor in diabetic illness and nor an important parameter in complications of diabetic diseases or in glucose metabolism imbalance. It is possible that the measurement of cellular glucose concentration gives a way to answer at the hypothesis that the magnesium has a role in the glucose metabolism.