Back
Acta Physiologica 2011; Volume 203, Supplement 686
Joint Congress of FEPS and Turkish Society of Physiological Sciences
9/3/2011-9/7/2011
Istanbul, Turkey
EFFECTS OF EXTREMELY LOW FREQUENCY (ELF) MAGNETIC FIELD ON THE OXIDATIVE STRESS PARAMETERS OF SOME INTERNAL ORGANS
Abstract number: PC249
Zulkuf Akdag1 Mehmet, Dasdag1 Suleyman, Erel2 Ozcan
1Department of Biophysics, Medical School of Dicle University, Diyarbakir, Turkey
2Department of Biochemistry, Medical School of Yildirim Beyazit University, Ankara, Turkey
Objective:
The aim of this study was to investigate the effect of 100 mT and 500 mT ELF magnetic field, on the oxidative stress parameters of some internal organs of rats.
Methods:
The study was carried out on 30 male SpragueDawley adult male rats. Rats in the first (n: 10) and the second (n: 10) experimental groups were respectively exposed to 100 mT and 500 mT ELF magnetic fields for 2 h/day for 10 months. At the end of the ten months of exposure some of the oxidative stress parameters such as catalase, myeloperoxidase, malondialdehyde (MDA), total oxidant status (TOS), total antioxidant capacity (TAC) and oxidative stress index (OSI) were measured in liver, lung and kidney of rats in the sham and two exposed groups.
Results:
Myeloperoxidase and OSI decreased in the kidney of the rat exposed to 100 mT and 500 mT ELF magnetic fields (p<0.05). However, increase of TAC in the kidney of rats exposed to 100 mT was found to be significant (p<0.05). By the way, decrease of TAC in the lung of the rats exposed to 500 mT ELF magnetic field was found significant (p<0.05). On the other hand, OSI decreased in the liver of rats exposed to 100 mT and 500 mT ELF magnetic fields while TAC increased in the liver of rats exposed to 100 mT magnetic field (p<0.05).
Conclusions:
Long-term exposure of 100 mT and 500 mT ELF magnetic fields can alter some of the oxidative stress parameters in the liver, lung and kidney of the rats.
To cite this abstract, please use the following information:
Acta Physiologica 2011; Volume 203, Supplement 686 :PC249