Objective: 

Running-walking and aerobic-steps are the most commonly used exercise methods. It has been demonstrated that exercise increases muscle derived cytokines (myokines) by increasing muscle size and decrease adipose tissue derived cytokins/hormones by reducing adipose tissue size. On the other hand, leptin, tumor necrosis factor-a, resistin and adiponectin secreted from fat tissue may have an effect on muscle tissue.

It was aimed to investigate whether IL-17 and myokines or adipokines were interrelated and to find out which type of aerobic exercise is more efficient on myokine and adipokine homeostasis in females. Any relationship between myokines, insulin resistance and low grade inflammations were investigated during exercise program.

Methods: 

Twenty five women were included in this study. They were assigned into two groups. One group (n=10) exercised by performing aerobic steps five days a week for ten weeks. The second group (n=15) exercised by performing running-walking for ten weeks. Serum IL-6, 15, 17,18, TNFa, leptin, adiponectin, and resistin levels were detected by ELISA on the blood samples taken before and 10 min and 2 hours after the study. Results were statistically analyzed and reported.

Results: 

TNFa, leptin, IL-15 and -18 levels of exercising aerobic-steps group differed significantly from that of walking-running groups. Differences between the levels of leptin, IL-15, and resistin before and after the exercise in running-walking group were found to be statistically signifant, wheras in aerobic steps group only TNFa level differed (p<0.05).

Conclusions: 

We suggest that running and walking exercises may influence myokine and lypokine systems more efficiently in women.