Objective: 

We aimed to evaluate the several blood parameters with respect to premenstrual syndrome during follicular and luteal phase.

Methods:In this study, adolescent girls ranged between 18–25 years were tested blood biochemical parameters in early follicular and late luteal phases. Their symptoms and complaints associated wtih Premenstrual Syndrome were assessed using Premenstrual Syndrome Scale. The statistical data analysis was performed using matched-pairs t-test, ANOVA, Tukey, Mann Whitney U, Kruskall Wallis.

Results: 

The leukocyte values were found higher in follicular phase than luteal phase (p<0.001). PMS has been found over 50% sample groups. The adolescent girls with first-degree obesity were determined to experience premenstrual syndrome more severely than the thin or normal-weight girls (p<0.05). In early follicular phase; adolescent girls with higher fasting blood glucose values were found to experience less fatigue while they suffer more sleep disorders with lower iron levels compared with higher levels. Adolescent girls with low or normal MEHC values struggled with more anxiety than ones with higher MEHC values (p<0.01).

Conclusions: 

This study has demonstrated that adolescent girls with iron insufficiency, low fasting blood glucose level and high body mass index experience the PMS symptoms more frequently. The presence of increased leukocyte values before menstrual cycle indicates that menstrual cycle is an associated condition with inflammation. This study reveals the importance of body mass index, anemia and controlling the blood glucose level in reducing PMS symptoms.