Acta Physiologica 2011; Volume 203, Supplement 686
Joint Congress of FEPS and Turkish Society of Physiological Sciences
AUTONOMIC DYSFUNCTION IN TEENAGERS WITH HIGH PREVALENCE OF ATHEROSCLEROTIC RISK FACTORS
Abstract number: PC065
Matei1 Daniela, Ignat2 Bogdan, Corciova3 Calin, Dinu Popescu2 Cristian, Zaharia3 Dan
1University of Medicine and Pharmacy Gr.T. Popa Iasi, Romania, Faculty of Biomedical Engineering, Biomedical Sciences
2University of Medicine and Pharmacy Gr.T. Popa Iasi, Romania, Faculty of General Medicine, Department of Neurology
3University of Medicine and Pharmacy Gr.T. Popa Iasi, Romania, Faculty of Biomedical Engineering, Biomedical Instrumentation
The aim of this study was to investigate autonomic cardiac control in teenagers with high prevalence of atherosclerotic risk factors.
Study was made on 25 subjects with the average age of 25±2.12 who have >=2 cardiovascular risk factors, one of them had to be major (smoking, high blood pressure, dyslipidemia) and antecedence in the family of diabetes mellitus and 25 normal subjects (control group). Using Biopac Acquisition System, we monitored the electrocardiogram, heart rate variability (HR) in basal condition and during a cold pressor test. From these measurements, HR variability parameters were calculated: low- and high-frequency bands LF and HF, LF/HF index), time-domain parameters (mean RR interval, SDNN, SDANN, SDNN index, rMSSD and pNN50%).
The teenagers with high prevalence of atherosclerotic risk factors had an increase in the mean heart rate at rest (P < 0.001), a decrease in standard deviation of R-R interval as well as in PNN50 (P < 0.001), and an increase in the LF/HF component ratio (P < 0.01) indicating a vagalsympathetic dysfunction in teenagers with atherosclerotic risk factors compare with control group.
Our results suggest a subclinical impaired of the autonomic nervous system in teenagers with high prevalence of atherosclerotic risk factors with marked parasympathetic dysfunction and sympathetic predominance.
To cite this abstract, please use the following information:
Acta Physiologica 2011; Volume 203, Supplement 686 :PC065