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Acta Physiologica Congress

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Acta Physiologica 2011; Volume 203, Supplement 686
Joint Congress of FEPS and Turkish Society of Physiological Sciences
9/3/2011-9/7/2011
Istanbul, Turkey


THE ROLE OF RESISTIN AND IL-6 IN THE METABOLIC SYNDROME
Abstract number: PC006

Ata1 Arif, Ergun2 Ahmet, Kenan Kose3 S

1Family Health Central veler, Ankara Turkey
2Department of Physiology Medical Faculty of Ankara University, Ankara Turkey
3Department of Biyoistatistik Medical Faculty of Ankara University, Ankara Turkey

Objective: 

The metabolic syndrome (MS) is a complex of symptoms that resulted from as a reply to inner and outer effects that influence the organism. Main components of MS are the obesity related to insulin resistance, dyslipidemia, hypertension, and hyperinsulinemia. It is considered that resistin and interleukin (IL)-6 are as effective on developing of insulin resistance and inflammation processes and there are a little studies on this subject

Methods: 

In our study, WC <=88 cm 22 women; <=102 cm 22 men; WC > 88 cm 20 women and > 102 cm 22 men were choosen from 86 subjects totally. According to ATP III criteria, results of mean cystolic and diastolic blood pressure, levels of fasting plasma glucose, fasting plasma insulin, total cholesterol, very low density lipoprotein cholesterol, triglyceride, plasma uric acid, resistin and IL-6 were compared each other statistically.

Results: 

In the group MS (+) mean systolic blood pressures (p <0,001), mean diastolic blood pressures (p <0,001), levels of mean fasting plasma glucose (p <0,05), mean fasting plasma insulin (p <0,05), total cholesterol (p <0,05), low density lipoprotein-cholesterol (p <0,05), very low density lipoprotein-cholesterol (p <0,001), triglyceride (p <0,001) acid were found high (p <0,001) compared with MS (-) group, and values of high density lipoprotein-cholesterol were found less than those.

Conclusions: 

In MS (+) group, hypertension, insulin resistance progress, dyslipidemia were found high by comparing with MS (-) group. Levels of plasma resistin and IL-6 were not statistically significant (p >0,05), compared with each others; however levels of IL-6 were found correlated with WC.

To cite this abstract, please use the following information:
Acta Physiologica 2011; Volume 203, Supplement 686 :PC006

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