Aims: 

There is only limited information available on the physiological function of the appendix testis (AT). Although AT is a remnant of the Mullerian duct, there is no information about AMH receptor expression in AT. Torsion of AT is painful and the symptoms are similar to that of the torsion of testis, so when an appendix appears in a surgery it is ablated. Recent studies show that the androgen receptor expression of AT is changing in connection with several urological disorders. In case of cryptorchidism AT is usually missing. This led us to propose that AT might take part in the migration of testis, and to suggest a connection between AMH receptor expression and some urological disorders. In these experiments, therefore, the expression of AMH receptor on AT was examined.

Methods: 

mRNA expression of the receptor was detected by RT-PCR, while immunohistochemistry was used to detect the expression of the protein. The tests were blind and more than one hundred samples were included for the statistical analysis.

Results: 

In regard to the patients' ages, the side of the diseases, the sizes of the malformations, we found that even though some tendencies could be observed, there were no significant correlations between the expression level of AMH receptor and the type of the urological disorder.

Conclusion: 

Both mRNA and protein expression of anti Mullerian hormone receptor was detectable in some appendix testis samples, however, this expression showed no correlation with the examined urological disorders.