Objective: 

The metabolic syndrome (MS) is a complex of symptoms that resulted from as a reply to inner and outer effects that influence the organism. Main components of MS are the obesity related to insulin resistance, dyslipidemia, hypertension, and hyperinsulinemia for compensation of hyperglycemia. It is considered that resistin and interleukin (IL)-6 are as effective on developing of insulin resistance and inflammation processes and there are a little studies on this subject.

Material and Methods: 

In our study, WC <=88 cm 22 women; <=102 cm 22 men; WC > 88 cm 20 women and > 102 cm 22 men were choosen from 86 subjects totally. According to ATP III criteria, results of mean cystolic and diastolic blood pressure, levels of fasting plasma glucose, fasting plasma insulin, total cholesterol, very low density lipoprotein cholesterol, triglyceride, plasma uric acide, resistin and IL-6 were compared each other statistically.

Results and Conclusion: 

In the group MS (+) mean systolic blood pressures (p <0.001), mean diastolic blood pressures (p <0.001), levels of mean fasting plasma glucose (p <0.05), mean fasting plasma insulin (p <0.05), total cholesterol (p <0.05), low density lipoprotein-cholesterol (p <0.05), very low density lipoprotein-cholesterol (p <0.001), triglyceride (p <0.001), plasma uric acid were found high (p <0.001) compared with MS (-) group. Values of high density lipoprotein-cholesterol were found less than those.

In MS (+) group, hypertension, insulin resistance progress, dyslipidemia, hyperurisemia were found high by comparing with MS (-) group. Levels of plasma resistin and IL-6 were not statistically significant (p >0,05), compared with each others; however levels of IL-6 were found correlated with WC.

Key Words: 

metabolic syndrome, waist circumference, lipid profile, resistin, IL-6