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Acta Physiologica Congress

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Acta Physiologica 2009; Volume 197, Supplement 675
Joint meeting of The Slovenian Physiological Society, The Austrian Physiological Society and The Federation of European Physiological Societies
11/12/2009-11/15/2009
Ljubljana, Slovenia


PATTERNS OF CARDIOVASCULAR CONTROL DURING REPEATED TESTS OF ORTHOSTATIC LOADING
Abstract number: L135

Joseph Batzel Jerry, Goswami1,2 Nandu, Karl Lackner2 Helmut, Roessler1 Andreas, Bachar4 Mostafa, Kappel3 Franz, Hinghofer-Szalkay1,2 Helmut

1Institute of Physiology, Center of Physiological Medicine, Medical University Graz, Austria
2Institute of Adaptive and Spaceflight Physiology, Wormgasse 9, Graz
3Institute for Mathematics and Scientific Computing, Karl Franzens, University, Graz, Austria
4Department of Mathematics, King Saud University, Saudi Arabia

To investigate patterns of cardiovascular control, a protocol of head up tilt (HUT) followed by lower body negative pressure (LBNP), which represents a significant cardiovascular control challenge, was employed. Linear regression of beat-to-beat heart rate and mean blood pressure data collected over repeated tests was used to analyze control response during the LBNP phase of the combined HUT-LBNP protocol. Four runs for each of 10 healthy young males reaching presyncope were analyzed. Subjects were classified into 2 groups based on the consistency of mean blood pressure (MBP) regulation in response to central hypovolemia induced by LBNP. The consistent group tended to exhibit consistent heart rate slope (rate of change of HR over time as calculated by linear regression) whereas subjects in the inconsistent group could not be easily classified. Subjects with consistent MBP maintenance exhibited patterns suggesting a consistency of response in cardiovascular control whereas subjects less successful in maintaining MBP exhibited less clearly defined patterns over four runs.

To cite this abstract, please use the following information:
Acta Physiologica 2009; Volume 197, Supplement 675 :L135

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