Central command activation and the exercise pressor reflex increase heart rate and arterial blood pressure during exercise. The contributions of cardiac output and total peripheral resistance to changes in arterial blood pressure differ between dynamic and static exercise. We investigated 10 healthy, supine volunteers by continuous measurement of heart rate, mean arterial blood pressure, stroke volume (ultrasound Doppler) and femoral beat volume (ultrasound Doppler) during both dynamic mild leg exercise and static forearm exercise. This made it possible to study cardiac output, femoral flow and both total and femoral peripheral resistance beat-by-beat. During a countdown-period, immediately prior to exercise, heart rate and mean arterial pressure increased, while stroke volume decreased. During mild supine exercise, stroke volume decreased. Dynamic leg exercise increased femoral beat volume, while static hand grip decreased femoral beat volume. Femoral flow is tightly regulated according to metabolic demand during both dynamic leg exercise and static forearm exercise. Our three major findings are, firstly, that stroke volume decreases during both dynamic and static exercise due to an increase in mean arterial pressure. Secondly, femoral beat volume decreases during static hand grip, but femoral flow is unchanged due to the increase in HR. Finally, central command activation is apparent prior to both dynamic and static exercise. Stroke volume should be included in future studies of central hemodynamics during exercise.