Abstract Index

Arthritis & Rheumatism, Volume 62,
November 2010 Abstract Supplement

Abstracts of the American College of
Rheumatology/Association of Rheumatology Health Professionals
Annual Scientific Meeting
Atlanta, Georgia November 6-11, 2010.

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Lack of Detection of Xenotropic Murine Leukemia Virus-Related Virus (XMRV) in Patients with Fibromyalgia.
Martin Jorge J. Gonzalez, Herrero-Beaumont Gabriel, Delgado Rafael

Lack of IL-17RA Signaling Prevents Autoimmune Inflammation of the Joint and Give Rise to a Th2-Like Phenotype in Collagen-Induced Arthritis.
Mus Anne-Marie, Corneth Odilia, Asmawidjaja Patrick, Lubberts Erik, MC Erasmus

Large Discrepancy between Expected and Observed Ratios of Biologic Treated Rheumatoid Arthritis Patients Also Compliant on DMARDs.
Choquette Denis, Arundine Mark, Thomas Oliver

Large-Scale Mapping of Systemic Lupus Erythematosus (SLE) Variants across Different Ethnicities Reveals That the IRF5-TNPO3 Region Is the Strongest Common Risk Factor.
Vyse Timothy J., Ramos Paula S., Kaufman Kenneth M., Kelly Jennifer A., Gallant Caroline, Delgado Angelica, Chung Sharon A., Criswell Lindsey A., Kimberly Robert P., Comeau Mary E., Williams Adrienne H., Russell Laurie P., Jacob Chaim O., Tsao Betty P., Alarcon-Riquelme Marta E., Moser Kathy L., Gaffney Patrick M., Harley John B., Langefeld Carl D.

Large-Vessel Involvement in Newly-Diagnosed Giant Cell Arteritis: A Case-Control Study Using Color-Doppler Sonography.
Ghinoi Alessandra, Boiardi Luigi, Pipitone Nicolò, Restuccia Giovanna, Nicolini Alberto, Silingardi Mauro, Germano Giuseppe, Bajocchi Gianluigi, Chiarolanza Ilaria, Magnani Luca, Macchioni Pierluigi, Caruso Andrea, Salvarani Carlo

Late Complement Complex in T Cell Function and Cell Death.
Chauhan Anil, Atkinson John P., Moore Terry L.

Lateral Compartment Unloading in People with Medial Knee Osteoarthritis.
Kumar Deepak, S. Rudolph Katherine, Manal Kurt

Lead and GoutGoing, Going Not Gone!
Krishnan Eswar, Lingala Bharathi, Fries James F., Bhalla Vivek

Leflunomide and the Risk of Hepatotoxicity: A Review of Post-Marketing Data.
Gilbert Jane L., Gelperin Kate, Lee Joann, Mishra Poonam, Choi Lauren, Brinker Allen, Graham David, Boucher Robert, Avigan Mark, Senior John

Leptin Promotes T Cell Autoimmunity through Modulation of the PKB/Akt/mTOR Pathway in Systemic Lupus Erythematosus (SLE) Patients.
Lourenco Elaine V., Hahn Bevra H., Iikuni Noriko, Kim Sarah J., Wong Maida, Singh Ram P., Grossman Jennifer, La Cava Antonio

Leukocyte Expression of Transcription Factor HNF4a, a Regulator of Gene Expression in Polyarticular Juvenile Idiopathic Arthritis.
Jiang Kaiyu, Chen Yanmin, Frank Mark Barton, Jarvis James N.

Level of Agreement of 1987 ACR and 2010 ACR/EULAR Classification Criteria: An Analysis Based on the ESPOIR Cohort Data.
Fautrel Bruno, Rincheval Nathalie, Combe Bernard G., Dougados Maxime, ESPOIR Scientific Committee 

Levels of beta2-Glycoprotein-I May Reflect a Protective Effect on the Development of Heart Block in Fetuses Exposed to Maternal Anti-Ro Antibodies.
Reed Joanne H., Gordon Tom P., Clancy Robert M., Buyon Jill P.

Levels of Soluble CD163 Is Associated with Disease Activity and Radiographic Progression in Early Rheumatoid Arthritis.
Greisen Stinne R., Hvid Malene, Stengaard-Pedersen Kristian, Hetland Merete L., Horslev-Petersen Kim, Moller Holger J., Deleuran Bent

Life Course Socioeconomic Position and Health Outcomes in People with Self-Reported Arthritis.
Shreffler Jack H., Schoster Britta, Martin Kathryn Remmes, Callahan Leigh F.

Life Expectancy, Standardized Mortality Ratios and Causes of Deaths of Six Rheumatic Diseases in Hong Kong, China.
Mok Chi Chiu, Kwok Raymond C. L., Ho Ling Yin, Chan Pak To, Yip Paul S. F.

Linking Power Doppler Ultrasound with Th17 Cells in the RA Joint.
Gullick Nicola J., Evans Hayley G., Church Leigh, Jayaraj David, Filer Andrew, Kirkham Bruce W., Taams Leonie S.

Lipid and C-Reactive Protein Screening Thresholds and CVD Risk in a Community Lupus Cohort.
Bartels Christie M., Buhr Kevin, Goldberg Jerry, Bell Carolyn, Greenlee Robert

Lipid and Inflammation Parameters: A Translational, Randomized Placebo-Controlled Study To Evaluate Effects of Tocilizumab: The MEASURE Study.
McInnes Iain B., Lee Janet S., Wu Wen, Giles Jon T., Bathon Joan M., Salmon Jane E., Beaulieu Andre D., Codding Christine E., Delles Christian, Sattar Naveed

Lipid-Cytokine-Chemokine Cascade Drives Neutrophil Recruitment in a Murine Model of Inflammatory Arthritis.
Kim Nancy D., Chou Richard C., Sadik Christian, Seung Edward, Lan Yinan, Iwakura Yoichiro, Luster Andrew

Liposomal Targeting of Glucocorticoids to the Synovial Lining during Experimental Arthritis Inhibits M1 Macrophage Activation in Favour of M2 Differentiation.
Hofkens Wouter, Storm Gert, Van Den Berg Wim B., van Lent Peter

LITHE: Tocilizumab (TCZ) Inhibits Radiographic Progression and Improves Physical Function in Rheumatoid Arthritis (RA) Patients (pts) at 3 Years with Maintenance of Clinical Efficacy over Time.
Kremer Joel M., Furst Daniel E., Burgos-Vargas Ruben, Dudler Jean, Mela Christopher M., Vernon Emma, Fleischmann Roy M.

Liver Injury in Patients with Rheumatic Diseases and Inflammatory Syndrome: A Case-Control Prospective Analysis Using Biomarkers (FibroTest, ActiTest and SteatoTest).
Gaujoux-Viala Cécile, Benhamou Mathilde, Munteanu Mona, Ngo Yen, Messous Djamila, Imbert-Bismut Françoise, Ratziu Vlad, Bourgeois Pierre, Poynard Thierry, Fautrel Bruno,  SAFE-T

Local Expression of IL-27 Reduces Collagen Induced Arthritis through Reduction of Monocyte Migration and Vascularization.
Pickens Sarah R., Volin Michael V., Mandelin Arthur M., Shahrara Shiva

Local TACI-Ig Gene Therapy of the Salivary Gland of NOD Mice Reduces Auto-Immune Inflammation by Affecting the B Cell Compartment.
Roescher Nienke, Vosters Jelle L., Guadagnoli Marco, Medema Jan P., Illei Gabor G., Chiorini John A., Tak Paul P.

Localized Scleroderma Therapy: When Would Be a Good Time To Stop?
Arkachaisri Thaschawee, Torok Kathryn S.

Long Term Profile of Cytokine, Metalloproteinase and Cartilage Biomarkers in Psoriatic Arthritis Patients Treated with Biologic Therapy.
Luis Fernandez-Sueiro Jose, Fernandez-Lopez J. C., Oreiro-Villar N., Pertega-Diaz S., Pinto J. A., Blanco FJ

Long Term Safety of an NSAID with Built-in Gastroprotection for Treatment of Pain and Inflammation Related to OA and RA: Results from a One Year Safety Trial of a Single-Tablet Combination of Ibuprofen-Famotidine vs. Ibuprofen Alone.
Schiff Michael H., Genovese Mark C., Kivitz Alan J., Bello Alfonso E., Sherman Jeffrey W., Grahn Amy, Weinblatt Michael E.

Long Term Treatment with Anakinra in Patients with Adult-Onset Still Disease.
Cecilia Giampietro, Meriem Ridene, Bruno Fautrel, Pierre Bourgeois

Longitudinal Assessment of Activity and Damage in a Synthetase Positive Cohort.
Cassidy Elaine A., Aggarwal Rohit, Fertig Noreen, Ascherman Dana P., Oddis Chester V.

Longitudinal Fatigue Severity Scale Scores Correlate with Modifiable Psychosocial Variables in Early Systemic Sclerosis.
Leyva Astrud Lorraine, Assassi Shervin, Mayes Maureen D., Nair Deepthi K., Fischbach Michael, Sharif Roozbeh, Reveille John D., Gonzalez Emilio B., McNearney Terry A.

Longitudinal Predictors of Progression of Subclinical Carotid Atherosclerosis in Rheumatoid Arthritis.
Giles Jon T., Post Wendy, Blumenthal Roger S., Polak Joseph, Petri Michelle A., Gelber Allan C., Szklo Moyses, Bathon Joan M.

Longitudinal Study on Growth Failure and Height Deflection in Juvenile Systemic Lupus Erythematosus (JSLE): The Result of a Prospective Multicentre PRINTO Study.
Rygg Marite, Pistorio Angela, Ravelli Angelo, Maghnie Mohamad, Iorgi Natascia Di, Demirkaya Erkan, Pasic Srdjan, Ozdogan Huri, Bader-Meunier Brigitte, Silva Carlos Henrique M. Da, Harel Liora, Molina Maria Rosa Roldan, Canhao Helena, Roth Johannes, Wouters Carine, Barash Judith, Ammar Rym Hajri Ben, Dracou Christina, Gandon-Laloum Sylvie, Martini Alberto, Ruperto Nicolino

Longitudinally Followed Serum Levels of B-Cell Activating Factor of the TNF Family Correlate with Disease Activity in Anti-Jo-1 Positive Patients with Myositis.
Krystufkova Olga, Mitterwald-Modra Marta, Mann Herman, Ekholm Louise, Hulejova Hana, Lundberg Ingrid E., Vencovsky Jiri

Long-Term Anti-CD20 Treatment Reduces Antibody-Secreting Ells in NZB/W Lupus Mouse.
Wang Wensheng, Owen Terasa, Ichikawa Travis, Anolik Jennifer H.

Long-Term Benefit of Mycophenolate Mofetil for Treatment of Diffuse Cutaneous Systemic Sclerosis.
Le Elizabeth, Wigley Fredrick M., Shah Ami A., Boin Francesco, Hummers Laura K.

Long-Term Denosumab Treatment of Postmenopausal Women with Osteoporosis: Results from the First Year Extension Study of the FREEDOM Trial.
Chapurlat Roland, Papapoulos Socrates, Bone Henry G., Brandi Maria L., Brown Jacques, Czerwinski Edward, Daizadeh Nadia S., Grauer Andreas, Haller Christine, Krieg Marc-Antoine, Libanati Cesar, Man Zulema, Mellstrom Dan, Radominski Sebastiao, Reginster Jean-Yves, Resch Heinrich, Ivorra Jose A. Roman, Cummings Steven R.

Long-Term Drug Survival of Anti-TNF Therapy in Ankylosing Spondylitis.
Li Qiang, Seah Michelle Y., Burgess John A., Dharmage Shyamali, Martin Belinda J., Buchanan Russell, Schachna Lionel

Long-Term Effect of Anti TNF-Alpha Therapies on Insulin Resistance, Body Composition and Adipokines in Rheumatoid Arthritis Patients.
Delgado-Frias Esmeralda, Hernandez-Hernandez Vanesa, Ferraz-Amaro Iván, Quevedo Juan Carlos, Muniz Jose R., Arce-Franco Maria T., Lopez-Fernandez Judith, Franco-Maside Andres, Diaz-Gonzalez Federico

Long-Term Efficacy of Tocilizumab (TCZ) in Patients (Pts) with Rheumatoid Arthritis (RA) Treated up to 3.7 Years.
Khraishi Majed, Alten Rieke, Gomez-Reino Juan J., Rizzo Warren, Schechtman Joy, Kahan Andre, Vernon Emma, Taylor Monet, Smolen Josef

Long-Term Follow Up of Hyper IgD Syndrome: A National Multicentre Study.
Federici Silvia, Tommasini Alberto, Meini Antonella, Calcagno Giuseppina, Zulian Francesco, Consolini Rita, Finetti Martina, Breda Luciana, Caorsi Roberta, Gallizzi Romina, Alessio Maria, Martini Alberto, Gattorno Marco

Long-Term Outcome of Autologous Hematopoietic Stem Cell Transplantation (AutoHSCT) Using Lymphoablative Conditioning in Treatment-Resistant Systemic Lupus Erythematosus.
Illei Gabor G., Hasni Sarfaraz A., Nikolov Nikolay P., Hakim Francis, Leitman Susan, Balow James, Austin Howard, Gea-Banacloche Juan, Oh Unsong, Odom Jeanie, Hardwick Donna, Sportes Claude, Gress Ronald, Pavletic Steven, Yarboro Cheryl, Muraro Paolo, Lipsky Peter

Long-Term Outcome of Patients with Juvenile Idiopathic Arthritis Treated with Etanercept Results of the Biologic Register JuMBO.
Minden Kirsten, Niewerth Martina, Zink Angela E., Seipelt Eva, Foeldvari Ivan, Girschick Hermann, Horneff Gerd

Long-Term Radiographic Outcome in Psoriatic Arthritis Patients Treated with Golimumab: 104 Week Results from the GO-REVEAL Study.
Kavanaugh Arthur, Van Der Heijde Desiree M., Gladman Dafna D., Mease Philip J., McInnes Iain B., Krueger Gerald G., Xu Weichun, Goldstein Neil, Beutler Anna

Long-Term Remission in Daily Clinical Practice: Excellent 2 Year Results with Treatment To Target in Very Early Rheumatoid Arthritis, Results of the DREAM Remission Induction Cohort.
Vermeer Marloes, Kuper Ina H., Hoekstra Monique, Moens Hein J. Bernelot, Posthumus Marcel D., Brus Herman L. M., van Riel Piet L. C. M., van de Laar Mart A. F. J.

Long-Term Safety of Abatacept: Integrated Analysis of Clinical Program Data of up to 7 Years of Treatment.
Hochberg Marc C., Westhovens Rene, Aranda Richard, Kelly Sheila M., Khan Nadar, Qi Keqin, Pappu Ramesh, Delaet Ingrid, Luo Allison, Torbeyns Anne, Moreland Larry W., Cohen Roger B., Gujrathi Sheila, Weinblatt Michael E.

Long-Term Safety of Rituximab: Follow-Up of the Rheumatoid Arthritis Clinical Trials and Retreatment Population.
van Vollenhoven Ronald, Emery Paul, Bingham Clifton O., Keystone Edward C., Fleischmann Roy M., Furst Daniel E., Macey Katherine, Sweetser Marianne, Lehane Patricia, Farmer Pam, Long Simon G.

Loss of Integrin alpha2beta1 Suppresses Joint Inflammation and Cartilage Destruction in Mouse Models of Rheumatoid Arthritis.
Peters Marvin A., Wendholt Doreen, Strietholt Simon, Frank Svetlana, Korb Adelheid, Joosten Leo A. B., Van Den Berg Wim B., Kollias George, Neumann Elena, Eckes Beate, Muller-Ladner Ulf, Pap Thomas

Loss of Microvascular Response to Central Nervous Impulses to Finger Pulp in Systemic Sclerosis.
Bergersen Tone Kristin, Hoffmann-Vold Anna-Maria, Midtvet Oivind, Gran Jan Tore, Mork Cato, Toska Karin

Low 25-OH Vitamin D Serum Levels Correlate with Extra-Hepatic Manifestations in Chronic Hepatitis C Virus Infection.
Terrier Benjamin, Souberbielle Jean-Claude, Saadoun David, Geri Guillaume, Schoindre Yoland, Sene Damien, Musset Lucile, Cacoub Patrice

Low Blood Concentration of Hydroxychloroquine Is Associated with Failure of Hydroxychloroquine Treatment in Patients with Cutaneous Lupus: Results of a Prospective Study.
Frances Camille, Cosnes Anne, Duhaut Pierre, Zahr Noël, Soutou Boutros, Oro Saskia, Bessis Didier, Chevrant-Breton Jacqueline, Cordel Nadege, Lipsker Dan, Costedoat-Chalumeau Nathalie

Low Bone Mineral Density in Depoprovera Users An Under Recognised Health Issue.
Nallasivan Mani, Gillott Tim

Low C4A Gene Copy Number in Systemic Lupus Erythematosus.
Pereira Kaline M. C., Faria Atila G. A., Moreira Eloisa S., Santos Viviane C., Grecco Marcelle, Silva Neusa P., Andrade Luis Eduardo C.

Low Doses of Etanercept Can Be Effective in Ankylosing Spondylitis Patients Who Achieve Remission of the Disease.
Navarro Compan Victoria, Ariza Ariza Rafael, Vargas Lebron Carmen, Hernandez Cruz Blanca, Moreira Navarrete Virginia, Navarro Sarabia Federico

Low Levels of Atheroprotective Natural IgM Antibodies Against Phosphorylcholine and Increased Prevalence of Vulnerable Atherosclerotic Plaques in Patients with SLE.
Anania Cristina, Gustafsson Thomas, Hua Xiang, Su Jun, Heimburger Mikael, Jogestrand Tomas, Frostegard Johan

Low Positive Affect Predicts the Development of Disability over 30-Months: The MOST Study.
Keysor Julie J., Fredman Lisa, Zhang Bin, White Daniel K., Torner James C., Lewis Cora E., Tolstykh Irina, Felson David T.

Low Prevalence of Coexistent Gout and Rheumatoid Arthritis in a Population of Veterans.
Tumyan Armine, Prescott Kara H., Reimold Andreas M.

Low Rate of Rheumatoid Arthritis Remission in Real Life: Might Predictive Factors Explain?
Loppin Elodie, Garlantezec Ronan, Solau-Gervais Elisabeth

Low Serum Levels of NT-proCNP in Children with Poly-Articular Onset Juvenile Rheumatoid Arthritis.
Khan Fozia, Pokelsek Ann, Galla Lori, Toth Mary, Bukulmez Hulya

Low-Dose Combination of Mycophenolate Mofetil and Tacrolimus for Refractory Lupus Nephritis: An Open-Labeled Trial.
Chiu Mok Chi, Hung To Chi, To Chan Pak, Lung Yu Ka, Yin Ho Ling

Low-Dose Glucocorticoid Chronotherapy of Rheumatoid Arthritis: 12 Week Efficacy and Safety of Modified-Release (MR) Prednisone.
Buttgereit Frank, Mehta Daksha P., Kirwan John R., Szechinski Jacek, Boers Maarten, Alten Rieke, Supronik Jerzy, Szombati István, Romer Ulrike, Witte Stephan, Grahn Amy, Saag Kenneth G.

Lower Body Mass Index Is Associated with an Increased Risk of Giant Cell Arteritis.
Jakobsson Karin, Jacobsson Lennart T. H., Warrington Kenneth J., Matteson Eric L., Liang Kimberly P., Melander Olle, Turesson Carl

Lower Education as a Proxy for Socioeconomic Status Is?Not Associated with Poor Outcomes in Systemic Sclerosis (SSc): Data from a Large SSc Cohort (Canadian Scleroderma Research Group).
Mansour Samah, Bonner Ashley, Baron Murray, Pope Janet E.

Lower Expression of Fli-1 Leads to Decreased Inflammatory Cell Infiltration in the Kidneys from NZM2410 Mice.
Williams Sarah, Reyes-Cortes Emmanuel, Karam Eva, Suzuki Eiji, Gilkeson Gary S., Zhang John

Lower Extremity Muscle Function, Quality of Life and Physical Function Outcomes and Their Relation to Subsequent Knee Replacement in a 24 Month PeriodData from the Osteoarthritis Initiative (OAI).
Buehring Bjoern, Bershadsky Boris, Husni M. Elaine

Lower Extremity Ulcers in Rheumatoid Arthritis.
DeMaria David M., Attinger Christopher E., Shanmugam Victoria K.

Lower Prevalence and Severity of Vulnerable Coronary Plaque in a-TNF-Exposed Asymptomatic Patients with Rheumatoid Arthritis (RA).
Karpouzas George A., Ahmadi Naser, Choi Tae-Young, Hajsadeghi Fereshteh, Munoz Silvia, Budoff Mathew

Lung Inflammation and Pulmonary Function Alterations in Collagen-Induced Arthritis and in the Absence of Interferon-gamma Signaling.
Schurgers Evelien, Mertens Freya, Vanoirbeek Jeroen, Mitera Tania, Put Stéphanie, Nemery Benoit, Matthys Patrick

Lupus Disease Severity Is Not a Risk for Cervical Intraepithelial Neoplasia in SLE.
Dhar J. Patricia, Gregoire Lucie, Lancaster Wayne, Stark Azadeh, Schwartz Ann, Schultz Daniel, Essenmacher Lynnette, Ager Joel, Chiodo Lisa, Husain Mujitaba, Sokol Robert J.

Lupus Immune Complex Gene Expression Arrays Reveal Divergent Pro- and Anti-Inflammatory Pathways Induced Depending on the Presence of Plasmacytoid Dendritic Cells and C1q.
Santer Deanna M., Elkon Keith B.

Lupus Nephritis: Decrease in Proteinuria and Sustained Stabilization of Disease Activity in Patients under Prolonged Immunoadsorption (IAS).
Stummvoll Georg H., Biesenbach Peter, Schmaldienst Sabine, Smolen Josef, Derfler Kurt

Lymph Node and Bone Marrow Expression of Macrophage Migration Inhibitory Factor and IL18 in Adult-Onset Still's Disease.
Park Sung-Hoon, Lee Hwa-Jeong, Kim Seong-Kyu, Choe Jung-Yoon

Lymphocytopenia and Infection Risk in Rheumatoid Arthritis: A Population Based Analysis.
Hoganson Deana D., Matteson Eric L., Fitz-Gibbon Patrick D., Crowson Cynthia S.

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