Arthritis & Rheumatism, Volume 63,
November 2011 Abstract Supplement

Abstracts of the American College of
Rheumatology/Association of Rheumatology Health Professionals
Annual Scientific Meeting
Chicago, Illinois November 4-9, 2011.

Hospitalization in Patients with Systemic Lupus Erythematosus.

Asiri1,  Alhussain, Gladman2,  Dafna D., MacKinnon1,  Anne G., Urowitz1,  Murray B.

Toronto Western Hospital and University of Toronto, Toronto, ON
Toronto Western Hospital, University of Toronto, Toronto, ON


Patients with SLE may require frequent admission to hospital. Understanding the characteristics and risk factors of hospital admission of lupus patients would allow effective planning of services and resources utilization. We aimed to identify the causes and risk factors for hospital admissions and re-admissions of lupus patients to a network of three large teaching hospitals, and the outcomes of those admissions.


Patients who were admitted to the between January 2009 and December 2010, who had a diagnosis of SLE were identified and their information collected from electronic patient record. Simple calculations for percentages and means and P-values were performed.


We identified a total number of 77 SLE patients admitted to hospital over the two year period with a total number of 165 admissions. SLE admissions represented 54% of total rheumatology admissions and 0.26% of total UHN admissions. The mean length of hospital stay in SLE patients was 14 days. When compared to patients in the lupus cohort seen during the same time period and not admitted to hospital, those admitted were more often Black, of younger age, shorter disease duration had a higher SLEDAI-2K and ACR/SLICC damage index. The main causes of admissions were disease flare 55 patients (71%) and infection in 16 patients (21%). Hospitalization outcome showed that in 27 patients (35%) the problem remained unresolved, 34 patients (46%) partially resolved and 14 patients (18%) had complete resolution of the primary problem. 22% had admission to ICU and 4% of patients died. 43 patients (56%) had re-admissions at least twice over 2 years. Mean hospital stay was 14 days for all admissions. Readmission causes were infections and non-resolved lupus flare in 44 % and 24 % respectively. Re-admissions for other medical or surgical causes accounted for 18% and 14% of the re-admissions respectively.


Admissions for SLE patients accounted for 54% of all rheumatology admissions. Major causes for admission are SLE flare and infection. There is a high rate of re-admission within a 2 year period. The major causes for re-admissions were infections and unresolved SLE flare. SLE patients utilize a significant proportion of rheumatology inpatient resources and services.

To cite this abstract, please use the following information:
Asiri, Alhussain, Gladman, Dafna D., MacKinnon, Anne G., Urowitz, Murray B.; Hospitalization in Patients with Systemic Lupus Erythematosus. [abstract]. Arthritis Rheum 2011;63 Suppl 10 :2285

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