Arthritis & Rheumatism, Volume 63,
November 2011 Abstract Supplement
Abstracts of the American College of
Rheumatology/Association of Rheumatology Health Professionals
Annual Scientific Meeting
Chicago, Illinois November 4-9, 2011.
The Relation Between Daily Physical Activity Measured with the Accelerometer and Clinical Assessments in Patients with Ankylosing Spondylitis.
Arends1, Suzanne, Hofman1, Marianne, Kamsma1, Yvo P.T., van der Veer1, Eveline, Leijsma1, Martha K., Houtman2, Pieternella M., Kallenberg1, Cees G.M.
Intervention studies concerning exercise programs and physical therapy in Ankylosing Spondylitis (AS) have revealed positive effects on clinical assessments of disease activity, physical function, and spinal mobility. Until now, data concerning the amount of daily physical activity (i.e. household, work, transport, and leisure time activities) in relation to these clinical assessments are lacking. The aim of the present study was to investigate the relation between daily physical activity and clinical assessments of disease activity, physical function, and spinal mobility in patients with AS.
Fifty-five Dutch AS outpatients were included. All patients were over 18 years of age and fulfilled the modified New York criteria for AS or the ASAS criteria for axial spondyloarthritis. Clinical assessments of disease activity (BASDAI, CRP, ESR, and ASDAS), physical function (BASFI), and spinal mobility (occiput-to-wall distance, chest expansion, modified Schober test, lateral spinal flexion, and cervical rotation) were administered at the outpatient clinic. In succession, daily physical activity was assessed using the ActiGraph accelerometer during 7 consecutive days. The outcome of the accelerometer was expressed in average kilo counts per day (kcounts/day). Pearson and Spearman correlations were calculated between accelerometer outcome and clinical assessments.
Mean age of the 55 AS patients was 44 years (SD±13), median disease duration was 17 years (range 254), and 62% were male. Median BASDAI was 3.2 (range 0.48.6), mean ASDAS was 2.2 (SD±1.0), and mean BASFI was 3.4 (SD±2.3), indicating mild disease activity and functional impairment. Daily physical activity, measured with the accelerometer, was negatively correlated with ESR (r=-0.460, p<0.001) and CRP (r=-0.279, p<0.05) and there was a trend suggesting a negative correlation with ASDAS (r=-0.257, p=0.061). Furthermore, daily physical activity negatively correlated with BASFI (r=-0.274, p<0.05) and positively correlated with the modified Schober test (r=0.338, p<0.05), lateral spinal flexion (left: r=0.344, p<0.05 and right: r=0.385, p<0.01), and cervical rotation (left: r=0.358, p<0.01 and right: r=0.285, p<0.05). No significant correlations were found between accelerometer outcome and BASDAI, occiput-to-wall distance, and chest expansion and accelerometer.
The present study indicates that higher daily physical activity, measured with the accelerometer, is related to lower disease activity, better physical function, and better spinal mobility in AS patients. Further studies are needed to investigate this relation.
To cite this abstract, please use the following information:
Arends, Suzanne, Hofman, Marianne, Kamsma, Yvo P.T., van der Veer, Eveline, Leijsma, Martha K., Houtman, Pieternella M., et al; The Relation Between Daily Physical Activity Measured with the Accelerometer and Clinical Assessments in Patients with Ankylosing Spondylitis. [abstract]. Arthritis Rheum 2011;63 Suppl 10 :1324