Arthritis & Rheumatism, Volume 62,
November 2010 Abstract Supplement
Abstracts of the American College of
Rheumatology/Association of Rheumatology Health Professionals
Annual Scientific Meeting
Atlanta, Georgia November 6-11, 2010.
Ultrasonographic Assessment of Hand Joint and Tendon Involvement in 30 Patients with Systemic Sclerosis.
Chatelus, Emmanuel, Chifflot, Hélène, Clavert, Viriginie, Sordet, Christelle, Gottenberg, Jacques-Eric, Sibilia, Jean
To evaluate joint and tendon involvement in the hands of patients with systemic sclerosis (SSc) using ultrasonography (US) and their correlation with clinical and X-ray examinations.
30 patients with SSc according to ACR criteria (21 diffuse SSc and 9 limited SSc, median (25th-75th) age 55 (4463) years, median (25th-75th) disease duration 5 (311) years, all negative for anti-CCP), were consecutively included in this study and underwent clinical, X-ray and US examinations. Synovial proliferation, joint effusion, bone erosion, tenosynovitis and the Power Doppler signal were evaluated using a Toshiba EUB-5500 with a 14 MHz linear-array transducer.
US detected synovial proliferation in 11 patients (37%), and joint effusion in 10 (33%). US detected synovitis in 47% of patients, higher than that found by clinical examination (27%; p=0.01), which was not associated with the radiological presence of erosion and joint space narrowing. Synovial proliferation and joint effusion were more frequent in diffuse SSc (43% for both) than in limited SSc (22%, 11%, respectively). Lastly, tenosynovitis (24%), bone erosion and Power Doppler (19%) were observed only in diffuse SSc.
US provides relevant information on the hands of patients with SSc that complements that obtained by clinical and X-ray examination. Also, diffuse SSc is a subgroup at greater risk of tendon and joint involvement. US evaluation may therefore be particularly helpful in detecting synovitis and bone erosion early in patients with diffuse SSc, and designing therapy.
To cite this abstract, please use the following information:
Chatelus, Emmanuel, Chifflot, Hélène, Clavert, Viriginie, Sordet, Christelle, Gottenberg, Jacques-Eric, Sibilia, Jean; Ultrasonographic Assessment of Hand Joint and Tendon Involvement in 30 Patients with Systemic Sclerosis. [abstract]. Arthritis Rheum 2010;62 Suppl 10 :1237